Article
The response to lovastatin treatment in patients with heterozygous familial hypercholesterolemia is modulated by apolipoprotein E polymorphism.
Metabolism: clinical and experimental - 1 Jul 1993
Carmena R, Roederer G, Mailloux H, Lussier-Cacan S, Davignon J
Abstract excerpt
In a retrospective study, we examined the influence of apolipoprotein (apo) E polymorphism and gender on the response to treatment with 80 mg/d lovastatin in a homogeneous population of patients with familial hypercholesterolemia (FH), most of whom were carriers of the 10-kb deletion of the low-d...
Topics
- Adult
- Apolipoproteins E
- Female
- Heterozygote
- Humans
- Hyperlipoproteinemia Type II
- Lipids
- Lovastatin
- Male
- Middle Aged
- Phenotype
- Polymorphism, Genetic
- Receptors, LDL
- Retrospective Studies