Article
Apolipoprotein E polymorphism and heterozygous familial hypercholesterolemia. Sex-specific effects.
Arteriosclerosis and thrombosis : a journal of vascular biology - 1 Oct 1994
Ferrières J, Sing C F, Roy M, Davignon J, Lussier-Cacan S
Abstract excerpt
The impact of apolipoprotein (apo) E polymorphism on interindividual variation in plasma lipid, lipoprotein, and apolipoprotein levels was studied in a sample of familial hypercholesterolemic (FH) patients (147 women, 116 men) with the same mutation, a > 10-kilobase deletion of the low-density li...
Topics
- Adult
- Alleles
- Apolipoproteins E
- Female
- Gene Deletion
- Genotype
- Heterozygote
- Humans
- Hyperlipoproteinemia Type II
- Male
- Polymorphism, Genetic
- Receptors, LDL
