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Article

Is the response of serum lipids and lipoproteins to postmenopausal hormone replacement therapy modified by ApoE genotype?

Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 1999

Heikkinen A M, Niskanen L, Ryynänen M, Komulainen M H, Tuppurainen M T, Parviainen M, Saarikoski S

Abstract excerpt

Postmenopausal hormone replacement therapy (HRT) has favorable effects on the serum lipid profile, and it also decreases the risk of cardiovascular diseases. The apolipoprotein E genotype has influence on serum levels of lipids and lipoproteins; apoE allele epsilon4 (apoE4) is associated with high total and LDL cholesterol levels. Genotype also influences the lipid responses to treatment with diet and statins,...

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Source

Identifiers

PMID: 9974425
DOI: 10.1161/01.atv.19.2.402

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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