Article
Effect of apolipoprotein E genotype on lipid levels and response to diet in familial hypercholesterolemia.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Feb 2000
Carmena-Ramón R, Real J T, Ascaso J F, Ordovás J M, Carmena R
Abstract excerpt
The response of plasma lipids to dietary fat and cholesterol is partly genetically controlled. Apolipoprotein (Apo) E polymorphism has been shown to influence basal plasma lipid levels and the response to dietary changes in normolipidemic individuals. In general, subjects carrying the E4 allele have higher basal total and low density lipoprotein cholesterol (LDL-C) plasma levels and show an increased LDL-C...
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