Article
Apolipoprotein E phenotypes in familial hypercholesterolaemia: importance for expression of disease and response to therapy.
Journal of internal medicine - 1 Feb 1993
Berglund L, Wiklund O, Eggertsen G, Olofsson S O, Eriksson M, Lindén T, Bondjers G, Angelin B
Abstract excerpt
To study the possible importance of variation at the apolipoprotein (apo) E gene locus for the clinical expression of heterozygous familial hypercholesterolaemia (FH), we determined apo E phenotype and serum lipoprotein pattern in 120 patients with FH. The allele frequency of the patients studies...
Topics
- Apolipoproteins E
- Cholestyramine Resin
- Double-Blind Method
- Humans
- Hyperlipoproteinemia Type II
- Lipids
- Phenotype
- Pravastatin
- Treatment Outcome