Article
The Caenorhabditis elegans unc-17 gene: a putative vesicular acetylcholine transporter.
Science (New York, N.Y.) - 30 Jul 1993
Alfonso A, Grundahl K, Duerr J S, Han H P, Rand J B
Abstract excerpt
Mutations in the unc-17 gene of the nematode Caenorhabditis elegans produce deficits in neuromuscular function. This gene was cloned and complementary DNAs were sequenced. On the basis of sequence similarity to mammalian vesicular transporters of biogenic amines and of localization to synaptic ve...
Topics
- Acetylcholine
- Alleles
- Amino Acid Sequence
- Animals
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Carrier Proteins
- Cloning, Molecular
- Genes, Helminth
- Helminth Proteins
- Membrane Transport Proteins
- Molecular Sequence Data
- Mutation
- Neurons
- Parasympathetic Nervous System
- Phenotype
- Sequence Alignment
- Synaptic Vesicles