Article
Genetic interactions between UNC-17/VAChT and a novel transmembrane protein in Caenorhabditis elegans.
Genetics - 1 Dec 2012
Mathews Eleanor A, Mullen Gregory P, Hodgkin Jonathan, Duerr Janet S, Rand James B
Abstract excerpt
The unc-17 gene encodes the vesicular acetylcholine transporter (VAChT) in Caenorhabditis elegans. unc-17 reduction-of-function mutants are small, slow growing, and uncoordinated. Several independent unc-17 alleles are associated with a glycine-to-arginine substitution (G347R), which introduces a positive charge in the ninth transmembrane domain (TMD) of UNC-17. To identify proteins that interact with...
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