Article
Benzyl-polyamines: novel, potent N-methyl-D-aspartate receptor antagonists.
The Journal of pharmacology and experimental therapeutics - 1 Nov 1997
Igarashi K, Shirahata A, Pahk A J, Kashiwagi K, Williams K
Abstract excerpt
The effects of benzyl-polyamines were studied at recombinant N-methyl-D-aspartate (NMDA) receptors expressed in Xenopus laevis oocytes. A number of mono-, di- and tri-benzyl polyamines, having benzyl substitutions on the terminal or central amino groups, inhibited responses of NR1/NR2 receptors i...
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