Article
Analysis of the anti-p53 antibody response in cancer patients.
Cancer research - 1 Aug 1993
Labrecque S, Naor N, Thomson D, Matlashewski G
Abstract excerpt
Mutations in the p53 tumor suppressor gene giving rise to mutant p53 proteins are among the most common genetic alterations associated with tumor cells. Mutant p53 gene products lose the wild type ability to suppress transformation in vitro or regulate cellular gene transcription. Mutant and wild...
Topics
- Antibodies, Neoplasm
- Breast Neoplasms
- Colonic Neoplasms
- Female
- Humans
- Lung Neoplasms
- Mutation
- Neoplasms
- Ovarian Neoplasms
- Protein Denaturation
- Tumor Suppressor Protein p53