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Article

A new set of monoclonal antibodies directed to proline-rich and central regions of p53.

Hybridoma and hybridomics - 1 Oct 2004

Voeltzel T, Morel A P, Rostan M C, Ji J, Chiodino C, Ponchel F, Vigouroux J, Caron de Fromentel Claude, Soussi T, Ozturk M

Abstract excerpt

The p53 protein can adopt several conformations in cells--"latent," "active," or mutant--depending on cellular stress or mutations of the TP53 gene. Today, only a few antibodies discriminating these conformations are available. We produced three new anti-p53 monoclonal antibodies (MAbs) directed against epitopes of human p53. The H53C1 MAb recognizes an epitope located at the N-terminal part of the central region...

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Identifiers

PMID: 15672606
DOI: 10.1089/hyb.2004.23.287

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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