Article
Deletion analysis of K+ channel assembly.
Neuron - 1 Jul 1993
Shen N V, Chen X, Boyer M M, Pfaffinger P J
Abstract excerpt
An understanding of K+ channel structure is a critical step in developing an appreciation of the function and regulation of these proteins. We have begun a biochemical analysis of the early steps in K+ channel formation following translation into endoplasmic reticulum membranes. In our experiments, a series of K+ channel subunit protein deletions were constructed and then tested for posttranslational processing...
Topics
- Animals
- Gene Deletion
- Mutation
- Oocytes
- Potassium Channels
- Protein Biosynthesis
- Protein Processing, Post-Translational
- Xenopus