Article
Pas de deux in groups of four--the biogenesis of KATP channels.
Journal of molecular and cellular cardiology - 1 Jun 2005
Neagoe Ioana, Schwappach Blanche
Abstract excerpt
The biogenesis of K(ATP) channels provides an interesting example of the assembly of structurally very different membrane protein subunits into a heterooligomeric complex. This review summarizes our current knowledge with respect to the protein domains driving heteromultimeric assembly in the endoplasmic reticulum, quality control, as well as the determinants and kinetics of subcellular sorting of the K(ATP)...
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