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Article

Sp1 is essential for both enhancer-mediated and basal activation of the TATA-less human adenosine deaminase promoter.

Nucleic acids research - 25 Feb 1994

Dusing M R, Wiginton D A

Abstract excerpt

Tissue-specific expression of the human adenosine deaminase (ADA) gene is mediated by transcriptional activation over a thousand-fold range. Cis-regulatory regions responsible for high and basal levels of activation include an enhancer and the proximal promoter region. While analyses of the T-cell specific enhancer have been carried out, detailed studies of the the promoter region or promoter-enhancer...

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Share to Electrophoresis, Polyacrylamide Gel
Share to Enhancer Elements, Genetic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 8127716
DOI: 10.1093/nar/22.4.669
PMCID: PMC307859

Genes

ADA
TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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