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Article

Prognostic significance of loss of heterozygosity at loci on chromosome 17p13.3-ter in sporadic breast cancer is evidence for a putative tumour suppressor gene.

British journal of cancer - 1 May 1999

Liscia D S, Morizio R, Venesio T, Palenzona C, Donadio M, Callahan R

Abstract excerpt

Several studies indicate that the short arm of chromosome 17 is one of the most frequently altered regions in sporadic breast carcinomas (45-60%). In the present report the 17p13.3-ter locus in tumour DNA of breast cancer patients, along with their matching normal lymphocyte DNA, have been mapped with four markers (D17S5, D17S379, ABR and D17S34), spanning nearly 3 cM of the telomer. Sixty-five of 143...

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Share to Carcinoma, Ductal, Breast
Share to Chromosomes, Human, Pair 17

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Genes, p53

Share to Genes, Tumor Suppressor

Share to Loss of Heterozygosity

Share to Multivariate Analysis

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Source

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Identifiers

PMID: 10360661
DOI: 10.1038/sj.bjc.6690427
PMCID: PMC2362303

Genes

ABR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Prognostic significance of loss of heterozygosity at loci on chromosome 17p13.3-ter in sporadic breast cancer is evidence for a putative tumour suppressor gene.PMID 10360661Read ↗

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