Article
p53 evaluation in gastric mucosa of patients with chronic Helicobacter pylori infection.
Anticancer research - 1 Jan 2000
Marinone C, Martinetti A, Mestriner M, Seregni E, Geuna M, Ferrari L, Strola G, Bonardi L, Fea E, Bombardieri E
Abstract excerpt
Gastric cancer is often associated with p53 over-expression and Helicobacter pylori (HP) infection. In this study we have investigated the production of the p53 protein and mutation of its gene in precancerous gastric lesions with HP infection. For this purpose 130 patients who underwent endoscopy for dyspepsia were enrolled in the study. To assess p53 production and mutation of the p53 gene we employed an...
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