Article
[Clinical importance of serum anti-p53 antibodies as tumor markers].
Rinsho byori. The Japanese journal of clinical pathology - 1 Oct 2002
Sakai Hiroshi, Okamoto Eiichi
Abstract excerpt
Anti-p53 antibodies are autoantibodies induced by mutation of p53 cancer-suppressor gene, and are considered to be indirect markers for p53 gene mutations and abnormally high p53 gene levels. We evaluated the usefulness of the measurement of anti-p53 antibodies by enzymed-linked immunosorbent assay using serum samples from patients with various disorders and normal subjects. The anti-p53 antibody concentration...
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