Article
HLA association of anti-Ro60 and anti-Ro52 antibodies in Sjögren's syndrome.
Journal of autoimmunity - 1 Oct 1994
Ricchiuti V, Isenberg D, Muller S
Abstract excerpt
The possible pathological role of antibody subsets specific for different regions of 60-KD and 52-KD Ro/SSA proteins (Ro60 and Ro52) and La protein is unclear. Previously, we have shown that in patients with Sjögren's syndrome, the fine specificity of Ro60 and Ro52 antibodies, as characterized with synthetic peptides, varied considerably according to the origin of sera. We therefore looked for possible...
Topics
- Adult
- Aged
- Aged, 80 and over
- Antibodies, Antinuclear
- Autoantigens
- Autoimmune Diseases
- Disease Susceptibility
- Epitopes
- Ethnicity
- Female
- Genetic Predisposition to Disease
- HLA Antigens
