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Article

Associations of MHC class II alleles in Norwegian primary Sjögren's syndrome patients: implications for development of autoantibodies to the Ro52 autoantigen.

Scandinavian journal of immunology - 1 Oct 2001

Nakken B, Jonsson R, Brokstad K A, Omholt K, Nerland A H, Haga H J, Halse A K

Abstract excerpt

Sjögren's syndrome (SS) is a chronic autoimmune disease characterized by dryness of the eyes and mouth. Currently, the highly polymorphic major histocompatibility complex (MHC) genes are the best documented genetic risk factor for the development of autoimmune disease. We examined the MHC class II alleles DRB1, DRB3, DRB4, DRB5, DQA1 and DQB1 in a group of Norwegian pSS patients and compared with a group of...

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Identifiers

PMID: 11555411
DOI: 10.1046/j.1365-3083.2001.00993.x

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