Article
Differential contribution of HLA-DR, DQ, and TAP2 alleles to systemic lupus erythematosus susceptibility in Spanish patients: role of TAP2*01 alleles in Ro autoantibody production.
Annals of the rheumatic diseases - 1 Apr 1998
Martín-Villa J M, Martínez-Laso J, Moreno-Pelayo M A, Castro-Panete M J, Martínez-Quiles N, Alvarez M, de Juan M D, Gómez-Reino J J, Arnaiz-Villena A
Abstract excerpt
OBJECTIVE: To study the influence MHC class II and TAP2 alleles exert on systemic lupus erythematosus (SLE) susceptibility and on the clinical and serological manifestations of the disease, in a cohort of Spanish patients. METHODS: HLA-DR serological typing and HLA-DQA, DQB, and TAP2 DNA sequence...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 3
- ATP-Binding Cassette Transporters
- Adult
- Alleles
- Antibodies, Antinuclear
- Antibody Formation
- Cohort Studies
- Disease Susceptibility
- Fluorescent Antibody Technique, Indirect
- HLA-DQ Antigens
- HLA-DR Antigens
- Histocompatibility Testing