Article
HLA-DRB genes and antiribosomal P antibodies in systemic lupus erythematosus.
British journal of rheumatology - 1 Dec 1994
Teh L S, Doherty D G, Williams B D
Abstract excerpt
Antibodies to the ribosomal P protein are specific for SLE but their prevalence varies in different ethnic groups. In a group of Chinese SLE patients from Malaysia who have a high prevalence of this antibody, we have found an increased frequency of an uncharacterized HLA-DRB gene allele, DR16X, in patients who are positive for anti-P antibodies compared to antibody negative patients (31.3% vs 3.2%, P < 0.01,...
Topics
- Alleles
- Antibodies
- Asian People
- China
- Complement C4
- Complement C4b
- Enzyme-Linked Immunosorbent Assay
- HLA-DQ Antigens
- HLA-DR Antigens
- Humans
- Lupus Erythematosus, Systemic
- Malaysia