Partial phenotypic reversion of HeLa cells by long-term interferon-alpha treatment.

doi:10.1089/jir.1993.13.369

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Article

Partial phenotypic reversion of HeLa cells by long-term interferon-alpha treatment.

Journal of interferon research - 1 Oct 1993

López Ocejo O, Perea S E, Reyes A, Vigoa L, López Saura P

Abstract excerpt

Human papillomaviruses (HPV) are associated with malignant cervical neoplasia. Several HPV-related diseases have been shown to be sensitive to interferon (IFN) treatment. HeLa cells contain and express the HPV type 18 genome and were used as a model for the evaluation of the viral expression regu...

Topics

2',5'-Oligoadenylate Synthetase
Animals
Cell Differentiation
Cell Division
Down-Regulation
Gene Expression Regulation, Viral
Genome, Viral
HeLa Cells
Humans
Interferon alpha-2
Interferon-alpha
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Nude

Papillomaviridae

Phenotype

RNA, Messenger

Receptors, Interferon

Recombinant Proteins

Source

Open in PubMed

Identifiers

PMID: 8301158
DOI: 10.1089/jir.1993.13.369

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8301158-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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