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Article

Effects of interferons alpha,beta,gamma alone or in combination on the phenotype of human colon carcinoma cells.

Anticancer research - 1 Jan 2000

Brouty-Boyé D, Maunoury M T, Lowy R

Abstract excerpt

The ability of interferons (IFNs) alpha,beta,gamma, alone or in combination, to induce reversion of the phenotype of cloned human colon carcinoma cells during long-term treatment was studied. The phenotypic characteristics examined were proliferation, cellular aggregation and tumorigenicity. The combination of IFN-beta and IFN-gamma showed more antiproliferative activity than that of IFN-delta and IFN-gamma or of...

Topics

Animals
Carcinoma
Cell Aggregation
Cell Division
Cell Line
Colonic Neoplasms
Drug Synergism
Humans
Immunotherapy
Interferons
Mice
Neoplasms, Experimental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 2451894

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2451894-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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