On the mechanism of phenotypic conversion of human cervical adenocarcinoma HeLa cells surviving infection by influenza B virus: potential implications for biological management of adenocarcinomas.

doi:10.1016/j.prp.2007.11.010

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Article

On the mechanism of phenotypic conversion of human cervical adenocarcinoma HeLa cells surviving infection by influenza B virus: potential implications for biological management of adenocarcinomas.

Pathology, research and practice - 1 Jan 2008

Sioutopoulou Despina O, Plakokefalos Elias, Arvanitis Leonidas, Athanassiou Evangelos, Venizelos John, Kaplanis Konstantinos, Destouni Chariclia, Nomikos Iakovos, Satra Maria, Vamvakopoulos Nicholas C

Abstract excerpt

We infected HeLa cells with low (10(-9) units), medium (10(-6) units), and high (10(-2) units) influenza B titers and compared the resulting human papilloma virus (HPV), retinoic acid receptor alpha subunit (RARalpha) and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA content of surviving infected hosts with that of their uninfected precursors by semi-quantitative reverse transcriptase/polymerase chain...

Topics

Adenocarcinoma
Antigens, Viral
Apoptosis
Cell Survival
Female
Gene Expression Regulation, Neoplastic
Gene Expression Regulation, Viral
Glyceraldehyde-3-Phosphate Dehydrogenases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

HeLa Cells

Human papillomavirus 18

Humans

Influenza B virus

Oncolytic Virotherapy

Oncolytic Viruses

Phenotype

RNA, Messenger

Receptors, Retinoic Acid

Retinoic Acid Receptor alpha

Source

Open in PubMed

Identifiers

PMID: 18291599
DOI: 10.1016/j.prp.2007.11.010

Genes

GAPDH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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