Modifying influence of prolonged action of interferon on phenotypic characteristics of human lung cancer cells in vitro.

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Article

Modifying influence of prolonged action of interferon on phenotypic characteristics of human lung cancer cells in vitro.

Experimental oncology - 1 Dec 2008

Kudryavets Yu I, Bezdenezhnykh N O, Lukyanova N Yu, Tregubova N A, Vorontsova A L

Abstract excerpt

AIM: To study modifying influence of interferon (IFN) on some phenotypic properties of human non-small-cell lung cancer cells (NSCLC) upon prolonged exposition of the cells with IFN. MATERIALS AND METHODS: A-549 cells were cultivated with IFN at increasing concentrations for a long period of time (up to 1 year). Cell morphology and ultrastructure were studied by light and electron microscopy. Expression of...

Topics

Antineoplastic Agents
Cadherins
Carcinoma, Non-Small-Cell Lung
Cell Line, Tumor
Cell Proliferation
ErbB Receptors
Humans
Immunohistochemistry
In Vitro Techniques
Interferons
Lung Neoplasms
Microscopy, Electron, Transmission
Phenotype
Vascular Endothelial Growth Factor A
Vimentin

Source

Open in PubMed

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PMID: 19112425

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