Article
Modifying influence of prolonged action of interferon on phenotypic characteristics of human lung cancer cells in vitro.
Experimental oncology - 1 Dec 2008
Kudryavets Yu I, Bezdenezhnykh N O, Lukyanova N Yu, Tregubova N A, Vorontsova A L
Abstract excerpt
AIM: To study modifying influence of interferon (IFN) on some phenotypic properties of human non-small-cell lung cancer cells (NSCLC) upon prolonged exposition of the cells with IFN. MATERIALS AND METHODS: A-549 cells were cultivated with IFN at increasing concentrations for a long period of time (up to 1 year). Cell morphology and ultrastructure were studied by light and electron microscopy. Expression of...
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