Article
The T-cell receptor V beta 6 gene usage in alloreactive T-cell responses.
Human immunology - 1 Jan 1995
Hu W, Weyand C M, Goronzy J J
Abstract excerpt
To analyze the role of TCR V beta gene elements in allorecognition, we have determined frequencies of the TCR V beta 6 elements expressed by allospecific T cells as compared to randomly activated T cells. Limiting dilution analysis was applied to estimate the usage of TCR V beta elements in CD4+ T cells polyclonally stimulated by immobilized anti-CD3 or specifically activated with HLA-DR disparate allotargets. In...
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