Article
The T-cell receptor V beta 6 gene usage in alloreactive T-cell responses.
Human immunology - 1 Jan 1995
Hu W, Weyand C M, Goronzy J J
Abstract excerpt
To analyze the role of TCR V beta gene elements in allorecognition, we have determined frequencies of the TCR V beta 6 elements expressed by allospecific T cells as compared to randomly activated T cells. Limiting dilution analysis was applied to estimate the usage of TCR V beta elements in CD4+...
Topics
- Alleles
- Amino Acid Sequence
- Antigen Presentation
- CD4-Positive T-Lymphocytes
- Cell Line
- Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
- HLA-DR Antigens
- HLA-DRB1 Chains
- Humans
- Interleukin-2
- Lymphocyte Activation
- Lymphocytes
- Molecular Sequence Data
- Receptors, Antigen, T-Cell, alpha-beta
- Sequence Alignment
- Sequence Homology, Amino Acid