Article
Allelic variations in the human T cell receptor V beta 6.7 gene products.
The Journal of experimental medicine - 1 Jan 1990
Li Y, Szabo P, Robinson M A, Dong B, Posnett D N
Abstract excerpt
Polymorphisms of human TCR gene products have been suggested by the description of a mAb, OT145, that identifies a subset of TCRs in some individuals but not in others (6). Here we demonstrate that this mAb detects a TCR allotype of the V beta 6.7 gene. Two allelic products of this V gene differ by two nonconservative amino acid substitutions. The mAb OT145 appears to react with V beta 6.7 a gene products ("+"...
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