Article
Allelic variations in the human T cell receptor V beta 6.7 gene products.
The Journal of experimental medicine - 1 Jan 1990
Li Y, Szabo P, Robinson M A, Dong B, Posnett D N
Abstract excerpt
Polymorphisms of human TCR gene products have been suggested by the description of a mAb, OT145, that identifies a subset of TCRs in some individuals but not in others (6). Here we demonstrate that this mAb detects a TCR allotype of the V beta 6.7 gene. Two allelic products of this V gene differ...
Topics
- Alleles
- Base Sequence
- Blotting, Southern
- Cell Line
- Cloning, Molecular
- DNA
- Genes
- Genetic Variation
- Haplotypes
- Humans
- Macromolecular Substances
- Molecular Sequence Data
- Oligonucleotide Probes
- Phenotype
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Receptors, Antigen, T-Cell
- Restriction Mapping