Silent allelic variants of a T-cell receptor V beta 12 gene are present in diverse human populations.

doi:10.1016/0198-8859(92)90112-z

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Article

Silent allelic variants of a T-cell receptor V beta 12 gene are present in diverse human populations.

Human immunology - 1 Jul 1992

Day C E, Zhao T, Robinson M A

Abstract excerpt

Amino acid substitutions in variable regions of the T-cell receptor (TCR) can alter T-cell reactivity; however, relatively little is known about the extent of allelic variation in human TCR coding sequences. In the present studies, coding region variation in the human TCR V beta 12.2 gene was exa...

Topics

Alleles
Amino Acid Sequence
Base Sequence
Chromosome Mapping
Cosmids
DNA
Female
Gene Frequency
Genetic Variation
Humans
Male
Molecular Sequence Data
Nucleic Acid Conformation
Pedigree
Receptors, Antigen, T-Cell, alpha-beta

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