Article
Silent allelic variants of a T-cell receptor V beta 12 gene are present in diverse human populations.
Human immunology - 1 Jul 1992
Day C E, Zhao T, Robinson M A
Abstract excerpt
Amino acid substitutions in variable regions of the T-cell receptor (TCR) can alter T-cell reactivity; however, relatively little is known about the extent of allelic variation in human TCR coding sequences. In the present studies, coding region variation in the human TCR V beta 12.2 gene was examined in detail. Virtually the entire V beta 12.2 coding region was screened for nucleotide substitutions by...
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