Article
Lymphocyte aging in bone marrow chimeras.
Growth, development, and aging : GDA - 1 Jan 1993
Armstrong M J, Janick-Buckner D, Harvey N, Briggs C J, Warner C M
Abstract excerpt
Chimeric mice provide a unique approach to the analysis of genetic factors associated with aging since cells with two genetically distinct backgrounds can be analyzed in the same animal. In this study, bone marrow chimeras were produced by reconstituting lethally irradiated female B6AF1 [(C57BL/6 female x A male)F1] mice with varying mixtures of T cell-depleted bone marrow cells from A (short-lived) and C57BL/6...
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