Article
Differential representation of B cell subsets in mixed bone marrow chimera mice due to expression of allelic variants of CD45 (CD45.1/CD45.2).
Journal of immunological methods - 31 Oct 2013
Basu Sreemanti, Ray Avijit, Dittel Bonnie N
Abstract excerpt
The CD45 congenic marker system is a highly utilized technique to track hematopoietic cells following bone marrow transplantation (BMT), with CD45.1 and CD45.2 being efficiently distinguished by flow cytometry. During the analysis of control mixed BM chimera mice in which lethally irradiated recipients were transplanted with an equal number of BM cells from WT CD45.1 and WT CD45.2 mice, we observed an unequal...
Topics
- Alleles
- Animals
- B-Lymphocyte Subsets
- Bone Marrow
- Bone Marrow Cells
- Bone Marrow Transplantation
- Chimera
- Leukocyte Common Antigens
- Mice
