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Article

Immunosenescence does not abrogate engraftment of murine allogeneic bone marrow.

Transplantation - 27 Jun 2013

Hock Karin, Oberhuber Rupert, Lee Ying-Lung, Wrba Fritz, Wekerle Thomas, Tullius Stefan G

Abstract excerpt

BACKGROUND: Allogeneic bone marrow transplantation is under investigation for a range of nonmalignant indications, including tolerance induction through mixed chimerism. This strategy has so far been tested experimentally only in young recipients. Due to immunosenescence, older patients have an increase in memory T cells (TMEM) as well as other alterations to their immune system, which may influence the potential...

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PMID: 23694950
DOI: 10.1097/TP.0b013e3182954618

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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