Mixed phenotype lymphomas in thymectomized (SL/KhxAKR/Ms)F1 mice.

doi:10.1111/j.1349-7006.1999.tb00699.x

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Article

Mixed phenotype lymphomas in thymectomized (SL/KhxAKR/Ms)F1 mice.

Japanese journal of cancer research : Gann - 1 Nov 1999

Lu L M, Hiai H

Abstract excerpt

Lymphomagenesis in mice is determined both by genetic and epigenetic mechanisms. The inbred strain SL/Kh mice selectively develop pre-B lymphomas and AKR/Ms, T-lymphomas. In crosses between SL/Kh and AKR/Ms, an AKR-derived dominant gene Tlsm1 (Thymic lymphoma susceptible mouse-1) determines the type of lymphoma to be a T-lymphoma. As an approach to the role of Tlsm1, we studied the effect of thymectomy at 1 week...

Topics

Animals
CD5 Antigens
Female
Flow Cytometry
Gene Rearrangement
Immunoglobulin M
Immunophenotyping
Leukocyte Common Antigens
Lymphoma
Lymphoma, B-Cell
Lymphoma, T-Cell
Male
Mice
Mice, Inbred Strains
Phenotype
Reverse Transcriptase Polymerase Chain Reaction
Thymectomy
Thymus Gland

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Identifiers

PMID: 10622532
DOI: 10.1111/j.1349-7006.1999.tb00699.x
PMCID: PMC5926021

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