Age-sensitive T cell phenotypes covary in genetically heterogeneous mice and predict early death from lymphoma.

doi:10.1093/geronj/49.6.b255

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Article

Age-sensitive T cell phenotypes covary in genetically heterogeneous mice and predict early death from lymphoma.

Journal of gerontology - 1 Nov 1994

Miller R A, Turke P, Chrisp C, Ruger J, Luciano A, Peterson J, Chalmers K, Gorgas G, VanCise S

Abstract excerpt

We have assessed several age-sensitive indicators of immune status in young (i.e., 6 to 11-month-old) mice of a genetically heterogeneous population to see if these varied in parallel and to determine if one or more of the status indices predicted life span or cancer incidence. We report that the...

Topics

Aging
Animals
CD4-Positive T-Lymphocytes
CD8-Positive T-Lymphocytes
Carrier Proteins
Cause of Death
Concanavalin A
Female
Hyaluronan Receptors
Immunologic Deficiency Syndromes
Immunologic Memory
Interleukin-2
Longevity
Lymphocyte Activation
Lymphoma

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Identifiers

PMID: 7525689
DOI: 10.1093/geronj/49.6.b255
PMCID: PMC7110387

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7525689-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Mice

Mice, Inbred AKR