Article
Age-sensitive T cell phenotypes covary in genetically heterogeneous mice and predict early death from lymphoma.
Journal of gerontology - 1 Nov 1994
Miller R A, Turke P, Chrisp C, Ruger J, Luciano A, Peterson J, Chalmers K, Gorgas G, VanCise S
Abstract excerpt
We have assessed several age-sensitive indicators of immune status in young (i.e., 6 to 11-month-old) mice of a genetically heterogeneous population to see if these varied in parallel and to determine if one or more of the status indices predicted life span or cancer incidence. We report that the number of memory (i.e., CD44hi) T cells within the CD8 subset is correlated with number of memory cells in the CD4...
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