Article
Identification of genomic regions required for DNA replication during Drosophila embryogenesis.
Genetics - 1 Nov 1993
Smith A V, King J A, Orr-Weaver T L
Abstract excerpt
A collection of Drosophila deficiency stocks was examined by bromodeoxyuridine (BrdU) labeling of embryos to analyze the DNA replication patterns in late embryogenesis. This permitted us to screen 34% of the genome for genes that when absent in homozygous deficiencies affect the cell cycle or DNA...
Topics
- Animals
- Cell Cycle
- Cyclins
- DNA Replication
- Drosophila melanogaster
- Gene Deletion
- Genes, Insect
- Genes, Lethal
- Genetic Complementation Test
- Phenotype
- Time Factors