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Regulation of DNA Replication in Early Embryonic Cleavages

19 Jan 2017

Abstract excerpt

Early embryonic cleavages are characterized by short and highly synchronous cell cycles made of alternating S- and M-phases with virtually absent gap phases. In this contracted cell cycle, the duration of DNA synthesis can be extraordinarily short. Depending on the organism, the whole genome of an embryo is replicated at a speed that is between 20 to 60 times faster than that of a somatic cell. Because...

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PMID: 28106858
DOI: 10.3390/genes8010042

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