Article
Suppressors of a lin-12 hypomorph define genes that interact with both lin-12 and glp-1 in Caenorhabditis elegans.
Genetics - 1 Nov 1993
Sundaram M, Greenwald I
Abstract excerpt
The lin-12 gene of Caenorhabditis elegans is thought to encode a receptor which mediates cell-cell interactions required to specify certain cell fates. Reversion of the egg-laying defective phenotype caused by a hypomorphic lin-12 allele identified rare extragenic suppressor mutations in five gen...
Topics
- Alleles
- Animals
- Caenorhabditis elegans
- Cell Communication
- Chromosome Mapping
- Disorders of Sex Development
- Female
- Genes, Helminth
- Male
- Mutation
- Oviposition
- Phenotype
- Suppression, Genetic