Article
HLA-DR/DQ gene variation in nongoitrous autoimmune thyroiditis at the serological and molecular level.
Autoimmunity - 1 Jan 1992
Bogner U, Badenhoop K, Peters H, Schmieg D, Mayr W R, Usadel K H, Schleusener H
Abstract excerpt
The etiology of autoimmune diseases is multifactorial with genetic factors being an important prerequisite. There are two clinical manifestations of autoimmune thyroiditis: the goitrous form (Hashimoto's thyroiditis) and the atrophic variant, which is characterized by hypothyroidism (primary myxo...
Topics
- Autoimmune Diseases
- Disease Susceptibility
- Female
- Genetic Markers
- Genetic Predisposition to Disease
- HLA Antigens
- HLA-DQ Antigens
- HLA-DR Antigens
- HLA-DR5 Antigen
- Humans
- Male
- Myxedema
