Article
HLA-DQB1-associated susceptibility that distinguishes Hashimoto's thyroiditis from Graves' disease in type I diabetic patients.
The Journal of clinical endocrinology and metabolism - 1 Apr 1994
Santamaria P, Barbosa J J, Lindstrom A L, Lemke T A, Goetz F C, Rich S S
Abstract excerpt
Insulin-dependent diabetes (IDDM) is frequently associated with autoimmune thyroid disease (ATD) within families. In these families, HLA polymorphism may modulate the susceptibility to each disease. Families with IDDM were further categorized as to the presence of ATD. IDDM-affected subjects from...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Autoimmune Diseases
- Diabetes Mellitus, Type 1
- Disease Susceptibility
- Female
- Graves Disease
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- HLA-DQ beta-Chains
- Haplotypes
- Humans
- Male
- Middle Aged
- Polymorphism, Genetic
- Thyroiditis, Autoimmune