Susceptibility and resistance alleles of human leukocyte antigen (HLA) DQA1 and HLA DQB1 are shared in endocrine autoimmune disease.

doi:10.1210/jcem.80.7.7608264

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Article

Susceptibility and resistance alleles of human leukocyte antigen (HLA) DQA1 and HLA DQB1 are shared in endocrine autoimmune disease.

The Journal of clinical endocrinology and metabolism - 1 Jul 1995

Badenhoop K, Walfish P G, Rau H, Fischer S, Nicolay A, Bogner U, Schleusener H, Usadel K H

Abstract excerpt

Because particular human leukocyte antigen (HLA) DQ alleles are the major predisposing factors for type 1 diabetes mellitus (IDDM), we investigated whether they are shared by other endocrine autoimmune diseases. We, therefore, analyzed the HLA DQ genotypes of 171 patients with IDDM, 271 with Graves' disease (GD), 65 with Hashimoto's thyroiditis, 51 with postpartum thyroiditis, 53 with Addison's disease (AD), and...

Topics

Addison Disease
Adolescent
Adult
Age of Onset
Alleles
Autoimmune Diseases
Base Sequence
DNA Primers
Diabetes Mellitus, Type 1
Disease Susceptibility
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, MHC Class II

Genetic Predisposition to Disease

Graves Disease

HLA-DQ Antigens

HLA-DQ alpha-Chains

HLA-DQ beta-Chains

Humans

Source

Open in PubMed

Identifiers

PMID: 7608264
DOI: 10.1210/jcem.80.7.7608264

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7608264-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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