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Article

Defects in heart and lung development in compound heterozygotes for two different targeted mutations at the N-myc locus.

Development (Cambridge, England) - 1 Oct 1993

Moens C B, Stanton B R, Parada L F, Rossant J

Abstract excerpt

Two types of mutant allele, one leaky and one null, have been generated by gene targeting at the N-myc locus in embryonic stem cells and the phenotypes of mice homozygous for these mutations have been described. These mutations have shown that N-myc has a number of functions during development, including a role in branching morphogenesis in the lung, which manifests itself at birth in mice homozygous for the...

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Identifiers

PMID: 8287798
DOI: 10.1242/dev.119.2.485

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Defects in heart and lung development in compound heterozygotes for two different targeted mutations at the N-myc locus.PMID 8287798Read ↗

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