Loss of N-myc function results in embryonic lethality and failure of the epithelial component of the embryo to develop.

doi:10.1101/gad.6.12a.2235

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Loss of N-myc function results in embryonic lethality and failure of the epithelial component of the embryo to develop.

Genes & development - 1 Dec 1992

Stanton B R, Perkins A S, Tessarollo L, Sassoon D A, Parada L F

Abstract excerpt

myc genes are thought to function in the processes of cellular proliferation and differentiation. To gain insight into the role of the N-myc gene during embryogenesis, we examined its expression in embryos during postimplantation development using RNA in situ hybridization. Tissue- and cell-specific patterns of expression unique to N-myc as compared with the related c-myc gene were observed. N-myc transcripts...

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Loss of N-myc function results in embryonic lethality and failure of the epithelial component of the embryo to develop.

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Loss of N-myc function results in embryonic lethality and failure of the epithelial component of the embryo to develop.

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