Article
Mutation of N-myc in mice: what does the phenotype tell us?
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Apr 1993
Davis A, Bradley A
Abstract excerpt
Oncogenesis is manifested as uncontrolled cellular proliferation and in some situations a failure of normal differentiation in the transformed cell. This has led to speculation that the normal role of proto-oncogenes during development may be to mediate the relationship between proliferation and...
Topics
- Animals
- Cell Differentiation
- Embryonic and Fetal Development
- Genes, Lethal
- Genes, myc
- Gestational Age
- Homozygote
- Mice
- Morphogenesis
- Mutagenesis
- Phenotype
- Proto-Oncogene Proteins c-myc
