Article
Two rhombomeres are altered in Hoxa-1 mutant mice.
Development (Cambridge, England) - 1 Oct 1993
Mark M, Lufkin T, Vonesch J L, Ruberte E, Olivo J C, Dollé P, Gorry P, Lumsden A, Chambon P
Abstract excerpt
This study provides a detailed description of the anatomical defects in the Hoxa-1-/- mutant mice previously generated in our laboratory (T. Lufkin, A. Dierich, M. LeMeur, M. Mark and P. Chambon, 1991; Cell 66, 1105-1119). Three-dimensional reconstructions of the Hoxa-1-/- rhombencephalon reveals...
Topics
- Animals
- Cranial Nerves
- Ear
- Image Processing, Computer-Assisted
- Immunoenzyme Techniques
- Mice
- Mice, Mutant Strains
- Morphogenesis
- Neural Crest
- Phenotype
- Rhombencephalon
