Article
Position effect variegation at fission yeast centromeres.
Cell - 14 Jan 1994
Allshire R C, Javerzat J P, Redhead N J, Cranston G
Abstract excerpt
Chromatin structure at Schizosaccharomyces pombe centromeres is unusual. The insertion of the ura4 gene within these centromeres resulted in genetically identical cells mosaic for its expression. Placement of the ade6 gene within cen1 or cen3 resulted in red-white sectored colonies, demonstrating the instability of gene expression. The occurrence of pink colonies implied that intermediate levels of repression...
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