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Article

Dependence of position-effect variegation in Drosophila on dose of a gene encoding an unusual zinc-finger protein.

Nature - 15 Mar 1990

Reuter G, Giarre M, Farah J, Gausz J, Spierer A, Spierer P

Abstract excerpt

Position-effect variegation is the inactivation in some cells of a gene translocated next to heterochromatin, the region of the chromosome that is permanently condensed. The number of copies of the Drosophila gene Suvar(3)7 is a dose-limiting factor in this phenomenon, and seems from its sequence that it encodes a protein with five widely spaced zinc-fingers. This novel arrangement of zinc-fingers could help in...

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PMID: 2107402
DOI: 10.1038/344219a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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