Article
Development of a neutralizing antibody response during acute primary human immunodeficiency virus type 1 infection and the emergence of antigenic variants.
Journal of virology - 1 Nov 1998
Lewis J, Balfe P, Arnold C, Kaye S, Tedder R S, McKeating J A
Abstract excerpt
We monitored the primary humoral response to human immunodeficiency virus type 1 infection and showed that, in addition to antibodies to p24 and gp41, antigens which form the basis of most diagnostic assays, the response included a significant antibody response directed to the gp120 region of the...
Topics
- Amino Acid Sequence
- Antigenic Variation
- Chimera
- Cytopathogenic Effect, Viral
- HIV Antibodies
- HIV Antigens
- HIV Core Protein p24
- HIV Envelope Protein gp120
- HIV Seropositivity
- HIV-1
- Humans
- Molecular Sequence Data
- Neutralization Tests
- Open Reading Frames
- Phenotype
