Article
Human immunodeficiency virus type 1 primary isolate neutralization resistance is associated with the syncytium-inducing phenotype and lower CD4 cell counts in subtype CRF01_AE-infected patients.
Journal of virology - 1 Aug 2003
Polonis Victoria R, de Souza Mark S, Darden Janice M, Chantakulkij Somsak, Chuenchitra Thippawan, Nitayaphan Sorachai, Brown Arthur E, Robb Merlin L, Birx Deborah L
Abstract excerpt
A number of human immunodeficiency virus type 1 (HIV-1) non-B-subtype products have been developed for present or future vaccine trials; in Thailand, several studies using subtype B and/or CRF01_AE vaccines have been conducted. To better characterize the biologic properties of these subtypes, 70 HIV-1 subtype B and E isolates were phenotyped as syncytium-inducing (SI) or non-syncytium-inducing (NSI) isolates and...
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