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Article

Inhibition of human O6-methylguanine-DNA methyltransferase by 5-methylcytosine.

Cancer research - 15 Jan 1994

Bentivegna S S, Bresnick E

Abstract excerpt

The ability of cloned human O6-methylguanine-DNA methyltransferase to repair a methylated guanine in a CpG-containing sequence, i.e., island, was studied by using a synthetic double-stranded 20-mer oligonucleotide from codon 248 of the p53 gene and another designed sequence. The double-stranded oligonucleotides incorporating 5-methylcytosine (5mC) and O6-methylguanine (O6mG) in various combinations in a CpG site...

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Identifiers

PMID: 8275462

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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