Article
Gene structure of CYP3A4, an adult-specific form of cytochrome P450 in human livers, and its transcriptional control.
European journal of biochemistry - 1 Dec 1993
Hashimoto H, Toide K, Kitamura R, Fujita M, Tagawa S, Itoh S, Kamataki T
Abstract excerpt
CYP3 A4 is the adult-specific form of cytochrome P450 in human livers [Komori, M., Nishio, K., Kitada, M., Shiramatsu, K., Muroya, K., Soma, M., Nagashima, K. & Kamataki, T. (1990) Biochemistry 29, 4430-4433]. The sequences of three genomic clones for CYP3A4 were analyzed for all exons, exon-intr...
Topics
- Adult
- Base Sequence
- Cells, Cultured
- Cytochrome P-450 CYP3A
- Cytochrome P-450 Enzyme System
- DNA
- Gene Expression Regulation, Enzymologic
- Humans
- Liver
- Mixed Function Oxygenases
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Promoter Regions, Genetic
- Sequence Deletion
- Transcription, Genetic
