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Article

Transcriptional regulation of the human cholesterol 7.alpha.-hydroxylase gene

10 Mar 1992

Abstract excerpt

As an initial step toward understanding the transcriptional regulation of cholesterol 7 alpha-hydroxylase (CYP7) in man, we isolated and functionally characterized the 5'-flanking region of the human CYP7 gene. The nucleotide sequences of the first exon and 1.6 kb preceding the exon were determined and found to contain a TATA box at position -30, a modified CAAT box at position -92, three potential hepatocyte...

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Identifiers

PMID: 1312351
DOI: 10.1021/bi00124a014

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