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Article

Characterization of the human protein S gene promoter: a possible role of transcription factors Sp1 and HNF3 in liver.

Thrombosis and haemostasis - 1 Dec 2003

Tatewaki Hideki, Tsuda Hiroko, Kanaji Taisuke, Yokoyama Kazunari, Hamasaki Naotaka

Abstract excerpt

Protein S is a vitamin-K-dependent plasma glycoprotein that serves as a cofactor for activated protein C in the protein C anticoagulation pathway, which regulates blood coagulation by inactivating factors Va and VIIIa. Mechanisms regulating the expression of the protein S gene remain unknown to date. The aim of this study was to characterize the cis-acting DNA elements of the human protein S gene in liver. We...

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PMID: 14652633
DOI: 10.1160/TH03-07-0443

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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